AffinityMap analyses maternal-fetal immunological compatibility by genotyping HLA-C and KIR genes. It assesses the risk of recurrent miscarriage, preeclampsia, and growth restriction due to immunological incompatibility, particularly when the embryo carries the paternal HLA-C2 allele and the maternal genotype is KIR AA.
Affinitymap is recommended for patients with recurrent miscarriage, implantation failure, or a history of or risk for preeclampsia, and can guide the selection of compatible sperm or egg donors.